This section enables the Administrator to configure which features and modules that the Administrator(s) want to use for their community website. There are also options to show and hide information from being viewed within the user interface. When you have a license to the software the serial number goes under General Setup.
IMPORTANT: It is very important not to change the Administrator name and email address if you already have a valid serial number without contacting your sales rep first. The setup options are organized by Modules to make it easier to navigate through the settings.

For more information on what each setup option does please navigate to the "Modules" section of the help document for detailed information